GW1516 (also known as Cardarine, Endurobol, and GW501516) it is a selective agonist of peroxisome proliferator-activator receptors (PPARs), not a steroid. It was originally developed for the treatment of obesity, diabetes mellitus, dyslipidemia, and cardiovascular diseases. GW1516 activates adenosine monophosphate-activated protein kinase (an enzyme involved in energy processes in our body also known as AMPK) and thus stimulates glucose uptake in skeletal muscle tissue. In studies, GW1516 demonstrated the ability to reverse the metabolic disorder in obese men with prediabetes syndrome, most likely by stimulating fatty acid oxidation.
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